However, after they were critically injured, both of them were experimented on against their will by scientists, and their genes were spliced during an experiment.

He began bonding with a hamster named Snowball. 3 Why does he always fail to take over the world?īrain came into being as an ordinary mouse, but he was imprisoned by scientists.

At one point he even tried to copy Orson's infamous radio telling of War of the Worlds. Brain is heavily based on Orson Welles, in both how he speaks and how he looks. However, this episode was non-canonical and was meant to joke on the WB's petty executives. In “ You'll Never Eat Food Pellets In This Town Again”, Brain has a wife named Sheila who apparently plays Billie. He strongly believes he can make the world a better place and that only he is intelligent enough to. He often thinks of complicated plans to take over the world. He has clearly shown he cares deeply for Pinky even going as far as giving up the world for him on multiple occasions, although he struggles to admit how much he really means to him. He is often annoyed by his companion Pinky's dim-witted thoughts and actions, although he is shown to really care for him. He's an intelligent, and megalomaniacal gene spliced lab mouse that harbors a long-lasting desire to take over the world. The Brain, or Brain for short, is one of the main characters of the Animaniacs franchise, serving as the anti-heroic main antagonist of the original show and its reboot, one of the major characters of Wakko's Wish, and one of the two titular main protagonists (alongside Pinky) of its spinoff Pinky and the Brain and Pinky, Elmyra and the Brain. Jean Claude Brain (parody of Jean Claude Giroux)īig Johnny Brain Jones Peachpit Bill Boone Crockett To become the leader/ruler of the world (failed)īrain Picadilly (parody of Brian Piccolo)īrainie the Poo (parody of Winnie the Pooh) White with pink ears, paws (hands), feet, and tail Lab mouse who is involved a laboratory plan to take over the world ' The same thing we do every night, Pinky.

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